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The Spark of Life
The Spark of Life
Jan 8, 2025 12:34 PM

Author:Frances Ashcroft

The Spark of Life

'A wonderful book' Bill Bryson

'Ashcroft achieves the sort of rich simplicity most science writers can only dream about ... this book carries the eponymous spark of life' Sunday Telegraph

From before birth to the last breath we draw, from consciousness to sexual attraction, fighting infection to the beating of our hearts, electricity is essential to everything we think and do.

In The Spark of Life award-winning physiologist Frances Ashcroft reveals the secrets of ion channels, which produce the electrical signals in our cells. Can someone really die of fright? How do cocaine, LSD and morphine work? Why do chilli peppers taste hot? Ashcroft explains all this and more with wit and clarity. Anyone who has ever wondered about what makes us human will find this book a revelation.

'A rare gift for making difficult subjects accessible and fascinating' Bill Bryson

'She communicates complex science with engaging passion and eloquence' Helen Dunmore, Observer

'Compelling and very readable, an excellent writer' Literary Review

'Riveting ... she has a stock of good tales' New Scientist

'Lively, conversational prose, refreshingly accessible to any lay reader ... a positively charged little book' Daily Telegraph

Frances Ashcroft is Professor of Physiology at the University of Oxford and a Fellow of Trinity College Oxford. She is also Director of OXION, a consortium of scientists studying ion channels, the heroes of this book. Her scientific research focuses on how a rise in your blood sugar level stimulates the release of insulin and what why this process goes wrong in diabetes. She has won many prizes for her research, most recently the L'Oreal/UNESCO 2012 Women in Science award. She is also a recipient of the Lewis Thomas Prize for Science Writing for The Spark of Life. Her first book for the general reader was Life at the Extremes: The Science of Survival.

Reviews

This is a wonderful book. Frances Ashcroft has a rare gift for making difficult subjects accessible and fascinating

—— Bill Bryson

One of the more momentous books of the decade

—— The New York Times Book Review

A lucid explanation of how to think probabilistically

—— Guardian

The inhabitants of Westminster are speed-reading The Signal and the Noise... They will find the book remarkable and rewarding

—— Sunday Telegraph

Is there anything now that Nate Silver could tell us that we wouldn't believe?

—— Jonathan Freedland

Fascinating... our age's Brunel

—— Bryan Appleyard , Sunday Times

A surprisingly accessible peek into the world of mathematical probability

—— Daily Telegraph

The Galileo of number crunchers

—— Independent

A 34-year old Delphic Oracle

—— Daily Beast

dense with details, rippling with insight an easy to read... This is everything we need to know.

—— William Leith , Evening Standard

An intense, fluid, intelligent, highly absorbing text that provokes vital questions about sustainability

—— Food Magazine

It's one of those rare books dense with detail, rippling with insight, and easy to read...This is everything we need to know

—— Johanna Thomas-Corr , Scotsman

In bringing food more directly onto the 'plate' of those who think about buildings and cities, she has done us all a great service

—— Richard Wilk , Building and Research Information

Emotional and resonant… Sharp, funny and sad in equal measure

—— Sally Morris , Daily Mail

Written with the same passion and wit that punctuated his reviews for the likes of NME, Coleman shares his journey to reconnecting with the soundtrack of his life

—— Big Issue in the North

I can’t tell you how good it is but I’ll try… It’s a superb analysis

—— William Leith , Evening Standard

A warm, witty and very candid book

—— Natasha Harding , Sun

The book offers experiences and, for anyone whose responsiveness to the world has slackened, a reminder of how full experience can be.

—— Amy Leach , Observer

Tim Dee has a deep feeling for the natural world and an ability to celebrate it in ways that seem fresh and new.

—— Tim Richardson , Literary Review

[Dee] writes so well, and so personably, that he casts a disarming spell over his readers.

—— Mary Blanche Ridge , Tablet

[Dee] is at once a naturalist, environmentalist, journalist, historian and diarist. Dee’s rich writing delights as he imparts his considerable research and observations about life and the state of the world

—— Good Book Guide

[It] belongs in the tradition of 'nature writing', but works with it too putting its beautifully written sentences in the service of description and evocation, but using them to frame a serious conversation about environmental preservation and its opposites; it’s a deeply attractive book and also an important one.

—— Andrew Motion , Guardian

Felt very deeply and pondered very wisely, it takes four areas of the planet and tells their story in ways that bring the plight (and delight) of the earth as a whole within reach.

—— Andrew Motion , Times Literary Supplement

A lyrical, poetic reflection on our relationship with the natural world.

—— Tim Maguire , Edinburgh Evening News

This profound work by Tim Dee is as creative and original as anything on the Man Booker shortlist and arguably more “useful”... The book’s reach is extraordinary.

—— Bel Mooney , Daily Mail

[A] marvellous new memoir.

—— Richard Mabey , New Statesman

An enthralling and unexpected book of what we have made of the natural world

—— Kathleen Jamie , Guardian

This is nature writing at its finest

—— Juanita Coulson , Lady

With the eye of a birdwatcher and the soul of a poet, Dee meditates on our green spaces and what we have made of them

—— Michael Kerr , Telegraph

Dee’s rich writing delights as he imparts his considerable research and observations about life and the state of the world

—— Good Book Guide

Charged with meaning and lyrically luminous, Four Fields is an unquantifiable work – and an unmissable one

—— Melissa Harrison , The Times
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